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They are the most popular doping substances. For example, the following substances are sold illegally online and elsewhere on the black market (well-known trade names given in parentheses): Nandrolone (Deca-Durabolin, Retabolin, Laurobolin), Metandienone (Dianabol, Danabol, Anabol, Metabolin), Stanotzolol (Stromba, Winstrol, Winstrol Depot), Trenbolone (Parabolan, Finajet), Oxymetholone (Anapolon, Anadrol, Androlic), Oxsandrolone (Anavar), Boldenone (Equipose), Fluoxymetsterone (Halotestin), Metenolone (Primobolan, Primobolan Depot), Testosterone and derivatives (Sustanon, Panteston). The main purpose of using these substances is to acquire a larger and better, more muscular appearance. Naturally, the fast results and slowdown in the development of muscle growth may act as motives for use. Improving sports results is the motive of people engaged in strength sports. Other motives include increasing the workout output, burning fat, slowing down ageing-related changes, and improving self-confidence and mood, among other things [8, 16, 17, 18, 19, 20]. Anabolic steroids are often used intermittently, buy arimidex 1 mg antiestrogens arimidex. The periods of use last from a few weeks to even years, but on average a few months. Often between the periods of use, breaks lasting a few months are taken. At the beginning of a period of use, the quantity of steroids is gradually increased and, toward the end of the period, steroid use is discontinued in steps over a period of one to two weeks. The purpose of the breaks is to reduce the adverse effects and to give the body’s hormone production time to recuperate. Another method of use is the so-called blast and cruise. The blast and cruise regimen involves the alternating use of higher (blast) and lower (cruise) doses. During a blast and cruise period, the use is continuous and no breaks are taken. Abuse is characterized by the excessive use of anabolic steroids and several different kinds of anabolic steroids at the same time (stacking) [8, 16, 17, 20, 21]. Oral anabolic steroids are used daily because of their fast half-life. Intramuscular anabolic steroids are often used weekly [22]. Medical anabolic steroid use seeks to attain the body’s physiological concentrations, but use for doping purposes often seeks concentrations that are approximately 40’100 times higher (supraphysiological levels) [8]. Since androgen receptors are widely found in the body, anabolic steroids affect the function of a number of different organs. This is why there are a number of potential adverse effects as well. Some of these effects are mild and temporary while others are life-threatening. The risk of adverse effects grows with the long-term use of high doses. There are a number of things that complicate the processes of studying the adverse effects of anabolic-androgenic steroids and obtaining scientific evidence. Firstly, the use of anabolic steroids is illegal in a number of countries, whereupon people are unlikely to say anything about anabolic steroid use. Secondly, because the substances are acquired on the black markets, users do not necessarily know what substances they are using or in what quantities.
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