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Consumption of supplements through a liposomal delivery system provides many scientific advantages, including biocompatibility, ability to carry large drug payloads, capacity for self-assembly, and a wide range of biophysical and physicochemical properties that have the ability to modify for control of biological characteristics. A very few number of nutritional supplement companies are relying on the benefits of liposomal delivery systems at this time. It’s well documented that the bioavailability of oral supplements is limited ‘ meaning we don’t really absorb all of the nutrition we consume. This makes most supplements a total waste of time and money. When you are checking out possible supplements for muscle growth and/or weight loss ‘ make sure they contain the liposomal delivery system to ensure you are going to actually absorb the substance in your body. It’s pretty simple: liposome delivery increases the amount of nutrition your body actually absorbs from the supplement. 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So let’s break down each of these compounds so you can see what they do, what they’re made of, and why you might consider taking this stack. DHEA is produced by our bodies naturally, and in the human body, DHEA is the most abundant steroid hormone in circulation. It is produced by the adrenal glands, the brain, and the gonads. In the brain, Dehydroepiandrosterone functions as a metabolic intermediate, responsible for biosynthesizing androgen and estrogen sex steroids. Although the research isn’t conclusive for all of these, DHEA has been used to improve physical performance, slow or reverse aging, improve cognitive skills of older people and slow the progress of Alzheimer’s, to treat sexual dysfunction, to improve sexuality in men and women, to prevent muscle damage from exercise, to treat metabolic syndrome, clogged arteries, depression, and if you can believe it, to treat a heck of a lot more conditions. I’ll go into the relevant science in a minute. But first, back to 1-DHEA. In the human body, 1-DHEA is converted into 1-testosterone (the prohormone steroid that was banned in 2005 by the FDA and DEA) through a two-step conversion via two enzyme pathways. This is because it doesn’t have the same estrogenic side effects as DHEA/5-DHEA that you don’t want to deal with. Because of this, it stacks well with other supplements to obtain gains in muscle tissue. Okay, back to the science. A 2013 study showed that 1-DHEA supplementation lead to significant increases in lean muscle mass, significant fat loss, and increased strength in the back-squat, bench press, and deadlift. The participants were given 330mg of 1-DHEA, spread across three doses each day, over the course of four weeks. Studies on glucose metabolism with rats shows that DHEA reduces body fat. The rats in the study were fed a high-fat diet with 1-DHEA supplements daily for a period of eight weeks. 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